Researchers have found that gut bacteria can interfere with the effectiveness of over 400 commonly used medications that ...

A new study shows how common gut bacteria can metabolize certain oral medications that target cellular receptors called GPCRs, potentially rendering these important drugs less effective.

Some gut bacteria could make medicines less effective and less likely to help make people better, researchers said this week.

Cell membrane proteins hide secret gateways that can be used to modify cell behavior. This has been demonstrated in a study ...

A new study, published today in Nature Chemistry by researchers from the University of Pittsburgh and Yale University, shows how common gut bacteria can metabolize certain oral medications that target ...

Common gut bacteria can metabolise some oral medications potentially rendering these important drugs against migraines, ...

In the inactive conformation, the a-subunit of the G protein binds to GDP and is bound to a beta-gamma complex (a). Upon receptor activation by its ligand, there is an exchange of GDP for GTP (b).

G-protein coupled receptors regulate hormone secretions in the pancreas. Learn how the complex signaling features of these receptors are illuminating diabetes research.

Tectonic is a clinical stage biotechnology company focused on the discovery and development of therapeutic proteins and antibodies that modulate the activity of GPCRs. Leveraging its proprietary ...

A study published in Nature Chemistry by researchers from the University of Pittsburgh and Yale University shows how common ...