and calcium sensing receptor family of GPCRs to dimerize. A number of studies have explored the effect of agonists on the level of receptor dimers and found that, in some cases, they stabilize and ...

cAMP, calcium and IP3 are the second messengers commonly assessed to follow GPCR activation. Drugs targeting GPCRs account for the majority of the best-selling drugs and about 40% of all ...

Current treatments mainly involve calcium and vitamin D supplementation ... which underscores the power of our Native Complex Platform to take on GPCR targets which have been historically ...

Review the complexities of Gq-coupled GPCR signaling cascades with a highlight on second messengers. Read analysis of the drawbacks of Calcium Flux technology and learn how to minimize false positives ...