G protein-coupled receptors (GPCRs) play a central role in the pathogenesis and development of osteoporosis, a serious bone metabolism-related disease.

With this knowledge, scientists are seeking to better understand the role of GPCRs in islet biology and hormone secretion, and how signaling in the cell through these receptors is disrupted in ...

more GPCR-targeted drugs can potentially be developed for the treatment of cancer and other diseases. Rebecca Roberts is a science writer and communicator. She earned her PhD in molecular biology from ...

Drugs that act on GPCRs, or G protein-coupled receptors, include more than 400 medications approved by the U.S. Food and Drug Administration (FDA) for the treatment of many common conditions such ...

Scientists from St. Jude Children's Research Hospital and the Medical College of Wisconsin have created a data science ...

“We have extensive experience in this emerging science; the revolution in GPCR structural biology has enabled significant advances in both biophysical methods and computational modelling of ...

They compared all human chemokine-binding GPCRs and all chemokines ... Department of Structural Biology. “The mix of those small packages from both the chemokine and receptor results in the unique ...

With approximately one third of all current FDA-approved drugs targeting GPCRs, Verily/Sosei Heptares ... Technological breakthroughs in molecular biology Kim was inspired by the “host of ...

Studies Kaposi’s sarcoma herpesvirus (KSHV) G protein-coupled receptor (GPCR) contribution to metabolic regulation, trafficking and signaling, using tissue culture models and molecular biology ...

Beyond creating significant value for Domain's pipeline, it demonstrates the Company's unparalleled expertise in GPCR biology, paving the way for novel treatments for complex diseases. Domain ...

Scientists have discovered how chemokines and G protein-coupled receptors selectively bind each other to control how cells move.