The commonly used Cockcroft-Gault method may result in excessive chemotherapy dosing — with potentially dire implications.

Some equations used to calculate estimated glomerular filtration rate (eGFR) may alter chemotherapy dosing in cancer patients ...

Abbreviations: GFR, glomerular filtration rate; CKD, chronic kidney disease; CVD, cardiovascular disease. Adapted from the National Kidney Foundation KDOQI Clinical Practice Guidelines for CKD.

and suggest that the National Kidney Foundation GFR threshold to define chronic kidney disease (<60 ml/min/1.73 m 2) might not be applicable in Indian populations.