Some equations used to calculate estimated glomerular filtration rate (eGFR) may alter chemotherapy dosing in cancer patients ...

They excluded patients with chronic kidney disease (CKD) stage 3 or higher. The early loss of renal function was defined as a loss in glomerular filtration rate (GFR) >3.3% per year. Of 355 ...

The commonly used Cockcroft-Gault method may result in excessive chemotherapy dosing — with potentially dire implications.

3 Other uses for GFR estimation equations include assessments of eligibility for Medicare reimbursement of treatment costs and for wait-listing for deceased-donor kidney transplantation.