Researchers reveal Prototaxites, a giant Devonian fossil, was not a fungus or plant but a unique extinct lineage.
Fungal infections are on the rise globally. According to a study by the Manchester Fungal Infection Group, in 2022, ...
Mandimycin, which targets a different essential fungi cell resource than other antifungal drugs, should harm other cell types as collateral — but doesn’t.
Read the paper: A polyene macrolide targeting phospholipids in the fungal cell membrane The human battle against harmful microorganisms has continued to rage in hospitals, clinics and communities ...
Though it’s a polyene, mandimycin has a unique mechanism for killing fungal cells: It binds to phospholipids in the fungal cell’s membrane, causing potassium to leak out of the cell and ...
Genomic changes in the infectious yeast Candida tropicalis may play a role in its resistance to antifungals, according to a ...