But she found no sign of SRY, nor the gene that substitutes for it. Instead, they discovered a tiny difference near the key ...

If the Y chromosome is present in the embryo's cells, a gene within the short arm of the chromosome called SRY will turn on, initiating a chemical chain reaction that will turn on other genes and ...

Background 46,XX testicular disorder of sex development is a rare genetic syndrome, characterized by a complete or partial mismatch between genetic sex and phenotypic sex, which results in ...

SRY expression is found in a specific subset of tyrosine hydroxylase-expressing neurons in the substantia nigra of males. Tyrosine hydroxylase affects synthesis of dopamine, a stimulatory ...

but it is only now that a non-mammalian candidate counterpart of Sry that is required for male development has been found. Matsuda and colleagues positionally cloned the sex-determining region by ...