They also found that the PlGF-induced increases in TNFα and IL-6 production may be caused by high levels of flt-1, a PlGF receptor, which are linked to the inflammatory response of RA patients.

The ability of tumours to induce new blood-vessel formation has been a major focus of cancer research over the past few decades, and vascular endothelial growth factor (VEGF) is now known to be ...

The primary clinical target of our VEGF-specific antibody programs was cancer ... few options were available at that time for wet AMD (Box 1). Visual acuity tests are the most common way to ...