This makes the Fugu genome a potentially powerful tool for functional gene analysis, he says, but scientists have until now been frustrated in their attempts to use them because mammalian cells do not ...

We describe here the development of a 12-color FISH assay for telomeric rearrangements ... The hybridization efficiency (defined as the percentage of cells with fluorescent signal on both sister ...

Therefore, an IHC result of 0/1+ cannot be completely considered as negative and the execution of a valid and complementary test, such as the FISH assay, is highly recommended to better define ...

Future Oncol. 2015;11(7):1023-1026. Tumor-negative breast cancers misclassified as HER2 negative by IHC (0 or 1+) could therefore be reclassified by FISH, with a remarkable impact on medical ...