Sphingosine is a membrane component in all cells and constitutes 25% of the lipid in the myelin sheath. Sphingosine is phosphorylated by ubiquitously expressed sphingosine kinases. S1P regulates ...

The latest judgments relate to an attempt by Chinese drugmaker HEC Pharma to bring a generic version of fingolimod to market in the US, and Novartis defense of the 9,187, 405 patent which expires ...

19 The first oral treatment, fingolimod, was introduced in 2010; it is also the only DMT approved for the treatment of MS in pediatric patients aged over 10 years. 19,22 Fingolimod is an analogue ...