Q: I was recently asked if I take a blood thinner. I wasn’t sure how to answer the question because I occasionally take ...

When blood clots, the soluble protein fibrinogen is converted into insoluble fibrin by the action of thrombin. The molecular events of the process have been traced in considerable detail ...

Blood clots are made up of two elements: platelets and fibrin. Platelets are cells produced in the bone marrow that travel throughout the bloodstream. When bleeding occurs, the platelets become ...

the stable fibrin clot being the final product of hemostasis. The fibrinolytic system then functions to break down fibrinogen and fibrin. Activation of the fibrinolytic system generates plasmin ...

TNKase is a lab-made version of a natural protein called tPA, which helps break down blood clots. It sticks to fibrin, the protein that holds clots together, and triggers an enzyme to dissolve them.

The drug works by breaking down fibrin, a component of blood clots. It is a modified version of a tissue plasminogen activator and helps blood flow freely again without causing systemic bleeding.