To showcase astrocytes’ role in memory, the Baylor team honed in on a gene called c-Fos, which plays an important role in neuron plasticity. The researchers found that about 4% to 5% of ...

The researchers show that during learning events, such as fear conditioning, a subset of astrocytes in the brain expresses the c-Fos gene. Astrocytes expressing c-Fos subsequently regulate circuit ...

They then tested these peptides in the neuronal Neuroscreen-1 (NS-1) cell line and the β-cell line INS1 to investigate their biological effects, focusing on their ability to induce Fos, a gene ...

Figure 4: Baclofen inhibits light-induced phosphorylation of histone H3 and induction of c-fos and Per1 gene expression in the SCN. Figure 5: Baclofen induces histone H3 phosphorylation and c-fos ...