When we think about what gets passed down from parent to child, most people imagine a mix, mum’s eyes, dad’s nose, a little ...

A recent publication in Genes & Diseases has delivered a compelling synthesis of the latest insights into the cellular ...

Overexpression of fibroblast growth factor receptor 3 (FGFR3) has been shown to drive oncogenesis in a subset of patients with multiple myeloma. However, epithelial cancers — such as bladder ...

The mutational spectrum of fibroblast growth factor receptor 3 (FGFR3) in individuals with achondroplasia ... developmental biology, gene regulation and epigenetics, cancer biology, immunity ...

The same gene can play "good cop, bad cop" – While FGFR3 gain-of-function variants cause achondroplasia, reduced FGFR3 activity has been linked to CATSHL syndrome, marked by unusually long limbs ...

Alterations in the FGFR3 gene are found in 15%-20% of advanced urothelial cancer cases. These mutations are particularly common in the luminal subtype of the disease. Clinical experts told NICE ...

Hypochondroplasia is a form of skeletal dysplasia caused by a defect in the FGFR3 gene that affects the conversion of cartilage into bone, resulting in shortened limbs and other complications ...

A recent publication in Genes & Diseases has delivered a compelling synthesis of the latest insights into the cellular ...