In the study, published March 14 in Science, the researchers found that linoleic acid can activate a major growth pathway in tumor cells by binding to a protein called FABP5. Comparing breast ...

This activation depends on a protein called FABP5, which acts as a lipid chaperone. When omega-6 linoleic acid binds to FABP5, it activates mTORC1, which then drives cell growth and proliferation.

In the study, published March 14 in Science, the researchers found that linoleic acid can activate a major growth pathway in tumor cells by binding to a protein called FABP5. Comparing breast ...

FABP5, sometimes referred to as epidermal FABP, was first discovered in psoriasis tissue in the early 1990s. It is highly expressed in skin and immune cells and plays a key role in skin cell ...

High expression of FABP5 promotes fatty acid metabolism through lipolysis and de novo fatty acid synthesis in prostate and breast cancer cells. Activation of PKC and increase in ROS levels by ...

The researchers found that linoleic acid binds to a protein called FABP5 (fatty acid-binding protein 5), which is at high levels in these cancer cells. In the new study, mice fed a high linoleic ...

In a new study, Yale researchers uncovered a key role played by a molecule called fatty acid binding protein 5 (FABP5) and found that inhibiting it blocked tumor progression in many cases.

In the study, published March 14 in Science, the researchers found that linoleic acid can activate a major growth pathway in tumor cells by binding to a protein called FABP5. Comparing breast ...

But how one disease predisposes to the other is unclear. In a new study, Yale researchers uncovered a key role played by a molecule called fatty acid binding protein 5 (FABP5) and found that ...