More information: Katlin H. Zent et al, Synapse-to-nucleus ERK-CREB transcriptional signaling requires dendrite-to-soma ...

Figure 4: Photic stimulation results in nuclear co-localization of P-ERK and P-CREB in the SCN. Figure 5: Glutamate triggers ERK activation in SCN slice and SCN-enriched primary neuron cultures.

They found that the effects were associated with the activation of CREB and extracellular signal-regulated kinase (ERK), two ...