Evidence presented supports a strong positive correlation between ERBB-2 overexpression and cyclooxygenase upregulation in human cholangiocarcinogenesis. Combination drug targeting of ERBB-2 and ...

Journal of Biological Chemistry 271, 5251–5257 (1996). Citri, A. et al. Hsp90 restrains ErbB-2/HER2 signalling by limiting heterodimer formation. EMBO reports 5, 1165–1170 (2004) doi ...

This attachment ultimately leads to propagation of the signal inside the cell and allows for multiple and varied cellular responses (Figure 2). ERBB receptors were discovered and characterized ...