Mpox, once a rare virus mainly confined to parts of Central Africa, is rapidly evolving into a more serious global health ...
Their paper is published in Molecular Psychiatry. The mutation increases levels of glycine decarboxylase, or GLDC, an enzyme ...
Life has evolved over billions of years, adapting to the changing environment. Similarly, enzymes—proteins that speed up ...
Enzymes initially developed in high-temperature environments and subsequently adapted to cooler conditions as the Earth underwent a cooling phase.
the field largely focused on it as the primary enzyme responsible for cancer mutations. But APOBEC3A—previously thought not to play such a prominent role—may actually be responsible for the mutations ...
Enzymes originally evolved in high-temperature environments and later adapted to lower temperatures as Earth cooled. Scientists discovered that a key shift in enzyme function occurred over ...
For instance, genes control the structure and effectiveness of digestive enzymes in your (and all other vertebrate) salivary glands. At first glance, mutations to salivary enzymes might appear to ...
Biology might ultimately provide a solution, however. Researchers have identified bacteria that evolved the ability to digest ...
Levels of active LRRK2 were high even in Parkinson’s patients without a mutation in LRRK2, suggesting that inhibitors of the protein could treat a wider patient population than expected. Originally ...
The mutation increases levels of glycine decarboxylase, or GLDC, an enzyme responsible for regulating glycine in the brain. Glycine activates receptors for the neurotransmitter glutamate ...