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Unlike unfractionated heparin (UFH), the low-molecular-weight heparin enoxaparin (Lovenox) is excreted mainly by the kidneys. To determine whether this characteristic heightens bleeding risk in ...
The second patient was a female with an admission weight of 180 kg and a BMI of 72 kg/m 2 who had an anti-factor Xa level of 0.55 IU/mL after the fourth dose of enoxaparin 90 mg. The dosage was ...
The patient’s weight of 125 pounds was reported as 125 kilograms — the equivalent of 275 pounds — in a pharmacy order for enoxaparin, an anticoagulant that is dosed based on patient weight.
When Momenta filed its ANDA for enoxaparin in August 2005, the challenge facing the FDA was how to demonstrate its therapeutic equivalence to Lovenox. The problem, ostensibly, is that enoxaparin ...
Recent data have shown that fondaparinux, a selective factor Xa inhibitor, is noninferior to enoxaparin for short-term prevention of adverse cardiovascular outcomes in patients with non-ST-segment ...