All patients received full therapeutic doses of enoxaparin or UFH. Renal insufficiency was mild (glomerular filtration rate, 41-60 mL/minute) in 50%, moderate (21-40 mL/minute) in 34%, and severe ...

RESULTS: A weight-based dosage range of enoxaparin 50–120 mg twice daily (median 60) was given to 23 patients. The mean BMI was 46.4 kg/m2. The initial mean anti-factor Xa level (measured after ...

The patient’s weight of 125 pounds was reported as 125 kilograms — the equivalent of 275 pounds — in a pharmacy order for enoxaparin, an anticoagulant that is dosed based on patient weight.

Recent data have shown that fondaparinux, a selective factor Xa inhibitor, is noninferior to enoxaparin for short-term prevention of adverse cardiovascular outcomes in patients with non-ST-segment ...

When Momenta filed its ANDA for enoxaparin in August 2005, the challenge facing the FDA was how to demonstrate its therapeutic equivalence to Lovenox. The problem, ostensibly, is that enoxaparin ...