Delta-like protein 4 (DLL4), also known as Drosophila Delta homolog 4 (Delta4), contains one DSL domain and eight EGF-like domains. It is expressed in vascular endothelium and functions as a Notch ...

To study the effects of blocking Dll4/Notch signaling in tumors, these authors developed a model in which C6 glioma tumor cells were transduced to express either soluble Dll4-Fc (C6 Dll4-Fc ...

First up is the company's big hope, the bispecific antibody CTX-009, now dubbed tovecimig, is a dual-targeted biologic that simultaneously binds the novel target DLL4, as well as VEGF. This dual ...

Tovecimig (DLL4 x VEGF-A bispecific antibody) met the primary endpoint in the ongoing randomized Phase 2/3 Study in patients with biliary tract cancer (BTC). Achieved a 17.1% overall response rate ...

Detailed price information for Compass Therapeutics Inc (CMPX-Q) from The Globe and Mail including charting and trades.