The nascent pri-microRNA (pri-miRNA) transcripts are first processed into approximately 70-nucleotide pre-miRNAs by Drosha inside the nucleus. Pre-miRNAs are transported to the cytoplasm by ...
Two inhibitors of the mammalian target of rapamycin (mTOR) pathway do little to slow the progression of a heritable kidney disorder called autosomal dominant polycystic kidney disease (ADPKD), a ...
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