In presence of exportin 5, the pre-miRNA is transported from the nucleus to the cytoplasm where the Dicer enzyme processes it into its mature form as miRNA. The miRNA is taken up into RISC and the ...
The double-stranded RNA is processed by an RNase III family enzyme Dicer, resulting in the generation of an siRNA, a 21–23-nucleotide (nt) RNA duplex, composed of a 19-mer sequence with ...
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