49). The function of this deacetylase is poorly understood, although region-specific and developmental expression patterns have been observed in the mouse brain 50. Recent progress in the field of ...

Growing evidence suggests that endometriosis is an epigenetic disease and, as such, could be treatable Many in vitro, in vivoand clinical studies have shown that histone deacetylase inhibitors ...

AC, acetylation; HDAC2, histone deacetylase 2; HIF-α, hypoxia-inducible factor 1-alpha; RCC, renal cell carcinoma; TGF-β, transforming growth factor-beta; TNF-α, tumor necrosis factor-alpha; VEGF, ...

Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...