This enzyme, also known as DPD, is usually caused by inherited changes in a particular gene. Currently, there are ...

Following conversion to 5-FU, 60–90% of capecitabine is catabolized by dihydropyrimidine dehydrogenase (DPD) ultimately to FBAL and 10–20% is excreted in urine unchanged. It has also been ...

Applied DNA Sciences shares are trading higher by 18.7% during Tuesday's session. The company announced it positioned its TR8 PGx testing as pre-emptive testing for therapeutic safety.

Company Revamps Pharmacogenomics Go-To-Market Strategy, Targets Validated PGx Assay Towards Specific Use Cases - Capecitabine and 5-FU are used for ... the absence of the DPD enzyme.