who demonstrated that TLR9 is absolutely required for all cellular responses to CpG DNA 2. The authors have shown that cells derived from TLR9-deficient mice are unresponsive to CpG stimulation.

ADA2, previously known for its role in catalyzing the deamination of adenosine to inosine, is revealed to function as an intracellular DNA-binding protein that controls TLR9 activation in ...

In the past decade, DNA vaccines have emerged as a potential favoured strategy for inducing immunity. Not only are they cost-effective and free of infection risk, but they can elicit both strong ...