Here, we show that solid-state nanopores can be used to directly observe individual knots in both linear and circular single DNA molecules of arbitrary length. The DNA knots are observed as short ...

First, linear folding paths were found to be preferable ... Following the design strategy, the team was able to create more complex DNA knots with increasing crossing numbers.

Just like any long polymer chain, DNA tends to form knots. Using technology that allows them to stretch DNA molecules and image the behavior of these knots, MIT researchers have discovered, for the ...

DNA is well-known for its double helix shape. But the human genome also contains more than 50,000 unusual knot-like DNA structures called i-motifs, researchers at the Garvan Institute of Medical ...

For the first time, scientists have detected a DNA structure inside living human cells that looks more like a four-stranded knot than the elegant double helix we learned about in school.

Animation of DNA’s knot-like i-motif structure the team mapped in 50,000 locations in the human genome, concentrated in key functional areas including regions that control gene activity Credit ...

Katherine Hignett is a reporter based in London. She currently covers current affairs, health and science. Prior to joining Newsweek in 2017, she edited a medicine industry newspaper and its ...

But scientists have long suspected there’s another type of DNA that looks quite different from the famous Watson-Crick model. They theorized that it’s knot-shaped, though they’d never ...

"The i-motif is a four-stranded 'knot' of DNA," says Marcel Dinger, co-lead researcher on the study. "In the knot structure, C letters on the same strand of DNA bind to each other – so this is ...

Even living cells have their own tangled problems to solve. They involve knots that arise accidentally in DNA and that can comprise its functionality. A new study by SISSA (Scuola Internazionale ...