They simply load somewhere on the DNA and start shaping it into a loop until they reach a point where they are forced to stop. That's why they rely heavily on the ability to explore both sides of ...

Figure 1: Schematic representation of the transition of a, the double helix into b, the two possible isomers of H-DNA. Figure 2: a, b, Sequential NOE interactions in the triplex loop and the 3 ...

The paper M. Ganji et al., “Real-time imaging of DNA loop extrusion by condensin,” Science, doi:10.1126/science.aar7831, 2018. How does a human cell neatly pack ...

A schematic showing how R-loops, a hybrid of RNA and DNA, can form during DNA transcription when the messenger RNA chain being assembled by the RNA polymerase binds to one of the DNA strands.

2008. Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures. Nature. 2008;453:489-494. Yang H, Zhou C, Dhar A, Pavletich NP. 2020. Mechanism of strand exchange from RecA-DNA ...