TGF-β and BMP bring about the recruitment of ligand-specific signal transducers (the SMAD proteins) to the pri-miR-21 transcript in complex with the RNA helicase DDX5 (p68). As a consequence ...

Supinoxin blocks SCLC progression through the DDX5 protein. Researchers in Tran's lab published results in 2020 showing that DDX5 helps support the cancer's malignant growth. DDX5 belongs to a ...