Designed to target cyclin E-driven cancers, NKT3964 is an oral small molecule offering substantial promise for addressing a ...

γ-herpesvirus genomes encode an abundance of homologues of cellular factors, including cyclin and Bcl-2. These viral homologues differ from their cellular counterparts in that the viral proteins ...

Which molecules involved in initiating centriole duplication are controlled by the cyclin–CDK complexes? Unfortunately, we still have very little information about these potential substrates.

"We are excited to outline a clear path for Zentalis to bring azenosertib to patients with Cyclin E1+ PROC,” said Ingmar Bruns, M.D., Chief Medical Officer. "In a patient population with a clear unmet ...