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Cyclin D1–CDK4/6 phosphorylates GTSE1 in cancer cells, preventing its degradation and sustaining high levels across the cell cycle, which enhances proliferation and correlates with poor prognosis.
Viruses are the masters of trickery. They mimic, manipulate and usurp cellular functions, but always with an interesting twist. γ-herpesvirus genomes encode an abundance of homologues of cellular ...
These changes were linked to decreased expression of a protein critical for cell division (cyclin D1) and increased expression of a protein that inhibits cell growth (p21). Infertility can ...