Some equations used to calculate estimated glomerular filtration rate (eGFR) may alter chemotherapy dosing in cancer patients ...

The commonly used Cockcroft-Gault method may result in excessive chemotherapy dosing — with potentially dire implications.

Conclusions The use of eGFR or CrCl to determine metformin eligibility instead of sCr can expand the adult population with diabetes for whom metformin is likely safe, particularly among non ...

The Rybrevant-Lazcluze combo significantly reduced the risk of death by 25% versus Tagrisso in patients with newly diagnosed advanced EGFR-mutated NSCLC, according to data from the phase 3 ...

Two studies examining relationships between measures of kidney function and adverse events after platinum-based chemotherapy were presented as late-breaking abstracts at the National Kidney Foundation ...

One of the early products of the Chronic Kidney Disease in Children (CKiD) study has been an updated equation for estimating GFR in children on the basis of demographic and laboratory parameters.

CrCl: 10–30mL/min: 250–500mg every 12 hrs ... Severe renal impairment (GFR <30mL/min): dose adjustment is usually needed. Elderly (consider monitoring renal function). Pregnancy.