In a recent study, FMI researchers have shed light on how intestinal organoids form crypts, the pockets that house stem cells ...

Caption A single human intestinal organoid, or HIO -- a hollow ball of cells grown from human embryonic stem cells and coaxed to become gut-lining cells. Scientists can use it to study basic gut ...

What am I looking at? This video shows actin at work in a growing intestinal organoid. The video is depth-coded for color, which means that cooler colors like blue and purple are closer to the viewer ...

Scientists turn to technologies that uplift organoid research, from the first intestinal organoids to the future of scaled-up screening. Disturbing circadian rhythms in organoids and mice increases ...

2 Intestinal Organoid Applications in Drug Screening New candidate drug screening for intestinal diseases is challenging due to toxicity and inconclusive results from traditional 2D cell culture and ...

Advances in three-dimensional organoid technology have revolutionized the stem cell field. Intestinal stem cells can be expanded and functionally differentiated to form “mini-organs” or organoids that ...

Researchers from the Organoid group at the Hubrecht Institute ... a specific type of cell in the intestinal lining that highly expresses CFTR, an important ion channel for electrolyte balance ...

Researchers from the Organoid group at the Hubrecht Institute have found that specific gut cells, BEST4/CA7+ cells, regulate electrolyte and water balance in response to bacterial toxins that ...

Our approach to organoid culture and differentiation involves the use ... and bond formation to study how intestinal stem cell colonies respond to alterations in geometric confinement, mirroring ...