murine mAbs were the predominant mAbs entering clinical studies, reaching a “peak” of eight products during the year 1991 (see Fig. 1). Chimeric mAbs were less evident: Between two and four ...

A multi-institutional team developed a chimeric antigen receptor (CAR ... "In our previous work in MM, we screened monoclonal antibodies (mAbs) to identify any that could react with human MM ...

Monoclonal antibodies (mAbs) and fusion (or chimeric) proteins that target proinflammatory cytokines have been used in the clinic for several rheumatic diseases, often with great success (a ...

"These chimeric models have become invaluable tools for neuroscience research," said Peng Jiang, an associate professor in the Department of Cell Biology and Neuroscience in the Rutgers School of ...

In an article published in Nature Cancer, a multi-institutional research team led by the University of Osaka describes how a molecule called HLA-DRB1 can be used as a target for chimeric antigen ...

In a recent article published in Nature Cancer, a multi-institutional research team led by The University of Osaka describes how a molecule called HLA-DRB1 can be used as a target for chimeric ...