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The data were classed by the year that the clinical studies were initiated, and by the specific mAb category (murine, chimeric, or humanized). Success rates were then calculated, being most ...
mAb therapy involves a range of mechanisms ... Some studies provide a rationale for translation of siltuximab (a chimeric anti IL-6) into the clinic in combination with melphalan-based therapies.
An international team of researchers co-led by UVA's Hui Li, PhD, looked at what are known as "chimeric RNA" in Chinese men and found both similarities and differences to those seen in Western men.
The results of Phase III trials of the CD20-targeted human monoclonal antibody (mAb) ofatumumab in rheumatoid arthritis and non-Hodgkin's lymphoma (NHL) dampen hopes on the potential of the drug ...
An international team of researchers co-led by UVA’s Hui Li, Ph.D., looked at what are known as “chimeric RNA” in Chinese men and found both similarities and differences to those seen in ...
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HLA-DRB1 molecule offers potential target for CAR therapy in relapsed acute myeloid leukemia post-transplantationIn an article published in Nature Cancer, a multi-institutional research team led by the University of Osaka describes how a molecule called HLA-DRB1 can be used as a target for chimeric antigen ...
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