CS was denatured at 50 μM (monomers) for 10 h in buffer B and diluted 100-fold into buffer A/10 mM Mg-acetate, containing chaperonin proteins at 25 °C. Aliquots were assayed for CS activity 54.

Disrupting the prefoldin chaperonin system both reduced mosquitoes' ability to host and transmit malaria parasites and killed ...

This strategy, pioneered by researchers at the Johns Hopkins Bloomberg School of Public Health, focuses on disrupting the protein quality-control system known as prefoldin chaperonin in Anopheles ...