Their research shows that fly Cdk8 and its human counterpart CDK19 have a role in regulating mitochondria, the powerhouses of the cell. Numerous studies have looked at ways to suppress ...

Selective inhibition of METTL3 enhanced anticancer activity via targeting the c-Myc pathway. Drugging the undruggable-targeting P53: A comparative analysis of APR-246 and coti-2 in human tumor primary ...

A major new study, published in Nature Chemical Biology today (Monday), announces the discovery of the first highly selective modulator of two proteins called CDK8 and CDK19—members of an ...

The molecular targets CDK8 and CDK19 – members of an important family known as kinases – have a key role in turning on cancer-causing genes and have been implicated in the development of several ...

Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. has synthesized cyclin-dependent kinase 8 (CDK8) and/or CDK19 inhibitors reported to be useful for the treatment of cancer. Shanghai ...

Insilico Medicine IP Ltd. has divulged cyclin-dependent kinase 8 (CDK8) and/or CDK19 dual inhibitors reported to be useful for the treatment of autoimmune diseases and cancer.

“This contributes to a lot of the cognitive losses and other disease symptoms.” Their research shows that fly Cdk8 and its human counterpart CDK19 have a role in regulating mitochondria, the ...