Vascularization plays a pivotal role, as inadequate blood supply can severely hinder healing. CD47, a protein present on nearly all human cells, has been linked to tissue regeneration and blood ...

More information: An antibody–toxin conjugate targeting CD47 linked to the bacterial toxin listeriolysin O for cancer ...

CD47-null femoral fractures show reduced bone formation, but increased tissue mineral density. µCT analysis of transverse femoral fracture in WT (n = 9) and CD47-null (n = 11-14) mice at ...

Just a week after dropping the development of its CD47-targeting antibody magrolimab in blood cancers, Gilead Sciences has paused enrolment in clinical trials of the drug in solid tumours ...

ImmuneOnco allocated a chunk of the money for the development and planned launch of IMM2520, a CD47×PD-L1 bispecific that it named as a key product. The biotech set aside a further 10% of its IPO ...

In reality, however, only apoptotic cells are engulfed, apparently because their surface ligand CD47 is prevented from activating the inhibitory phagocyte receptor SIRPα. Figure 2: Formation of a ...

A new study from the USC Norris Comprehensive Cancer Center has found evidence that targeting CD47, a protein that is part of the innate immune system, could be a key step in fighting colorectal ...