OncoImmune has a robust pipeline, deep biology insights into CD24–Siglec and CTLA-4 signaling, and a very flexible approach to partnering. It is looking for strategic partners and/or investors ...

Interestingly, CTLA-4 knockout mice and mice that lack expression of CTLA-4 just in T REG develop fatal, early-onset lymphoproliferative disease. 1,4 In addition, expression and signaling of CTLA ...

An important inhibitory molecule expressed by dendritic cells is Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4). Our lab has shown that DC CTLA-4 is expressed and secreted in extracellular ...

GT-008 is a first-in-class, glycan-dependent monoclonal antibody targeting CD24, a surface protein implicated in tumor progression. By recognizing a tumor-associated O-glycoform of CD24—limited in ...

Adagene Inc. announced a poster presentation for the ASCO 2025 conference in Chicago, highlighting the safety and efficacy of its product, ADG126, an anti-CTLA-4 masking antibody, in combination ...

Cadonilimab plus lenvatinib showed promising antitumor activity in patients with advanced endometrial cancer who have experienced disease progression after prior platinum-based chemotherapy,” said ...