Caspase-3 is a prototypical group II effector caspase that can be activated by both the receptor and mitochondria-mediated pathways. Mice deficient in caspase-3 (caspase-3 −/−) have defective ...

Elevated p62 levels were seen alongside a rise in caspase-3, an enzyme that plays a key role in apoptosis or cellular self-destruction, likely due to cold-induced stress. While autophagy and ...

In vivo animal experiments demonstrated that L-AuNP@TMT induced ICD and caspase-3/GSDME-mediated cellular pyroptosis in tumor cells under near-infrared irradiation, thereby activating the body's ...

PODO Therapeutics will showcase two poster presentations highlighting its innovative platform at the upcoming AACR Annual ...

For example, researchers will measure cell death to determine a drug’s anticancer effectiveness. Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark ...