New insights into the mechanisms that cause more severe cases of schistosomiasis - a disease caused by parasitic worms and ...

the researchers also found that caspase-1 and caspase-8 were key in activating these inflammasomes. These enzymes also helped ...

burns 8, endotoxemia 9 and sepsis 10 after administration of drugs that block caspases. Caspase-3 is a prototypical group II effector caspase that can be activated by both the receptor and ...

For example, researchers will measure cell death to determine a drug’s anticancer effectiveness. Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark ...