L'équipe du professeur Jean-Bernard Denault, de la Faculté de médecine et des sciences de la santé, a démontré le rôle de la caspase 7, une enzyme, dans les mécanismes qui gèrent la durée de vie d'une ...

caspase-6, nuclear lamin, DNA-dependent protein kinase, and DNA fragmentation factor 45 (DFF45 or ICAD) 7. In particular, degradation of DFF45 releases its inhibition of DFF40 (or CAD), which ...

was treated with either the diluent in which the caspase inhibitor was prepared or, in some instances, M-725 (the inactive diastereomer of M-920). Survival was recorded for 7 days. Tissue sections ...

For example, researchers will measure cell death to determine a drug’s anticancer effectiveness. Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark ...