Caspase-3 is a prototypical group II effector caspase that can be activated by both the receptor and mitochondria-mediated pathways. Mice deficient in caspase-3 (caspase-3 −/−) have defective ...

The following is a summary of "Enhanced anticancer efficacy of oxaliplatin-loaded PEGylated niosomes in breast cancer treatment," published in the April 2025 issue of Cancer Nanotechnology by ...

Elevated p62 levels were seen alongside a rise in caspase-3, an enzyme that plays a key role in apoptosis or cellular self-destruction, likely due to cold-induced stress. While autophagy and ...

PODO Therapeutics will showcase two poster presentations highlighting its innovative platform at the upcoming AACR Annual ...

For example, researchers will measure cell death to determine a drug’s anticancer effectiveness. Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark ...