Caspase-3 is a prototypical group II effector caspase that can be activated by both the receptor and mitochondria-mediated pathways. Mice deficient in caspase-3 (caspase-3 −/−) have defective ...

A new study reveals some surprising discoveries about healing processes that are potentially triggered by the process of ...

A systematic review published in Discover Oncology explores the anticancer efficacy of medicinal plant extracts in treating Oral Squamous Cell Carcinoma (O | Plants And Animals ...

For example, researchers will measure cell death to determine a drug’s anticancer effectiveness. Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark ...

Macrophages control intracellular pathogens like Salmonella by using two caspase enzymes at different times during infection.

A necrotic Drosophila wing imaginal disc undergoing regeneration, showing NiA/NiCP (white) cells at a distance from the injury (green: GFP-labeled wing pouch cells, red: necrotic wound, white: caspase ...

This focus has evolved to include the investigation of non-apoptotic functions of proteins that have long been considered to have roles in apoptosis, the caspase family of proteases. Our research ...