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Researchers have developed a machine learning model that predicts Cas9 proteins that can be tailored with designer properties for therapeutic use.
The Cas9 protein is the most widely used by scientists. This protein can easily be programmed to find and bind to almost any desired target sequence, simply by giving it a piece of RNA to guide it ...
A new set of genes that contribute to Parkinson’s disease risk has been identified.
CRISPR-Cas9 is not the first method available to scientists for modifying DNA; it is by far, however, the easiest to use. With CRISPR-Cas9, the crRNA/tracrRNA sequence or an artificial guide RNA ...
CRISPR/Cas9 remains the most powerful tool to generate ... To put it in numbers: with their previous vector, a CRISPR screen looking for all double knockouts of just 20 genes was estimated to ...
In December 2020, the New England Journal of Medicine published a paper titled CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia, marking an exciting new chapter in the treatment of ...