Researchers have developed a machine learning model that predicts Cas9 proteins that can be tailored with designer properties for therapeutic use.

In their new work, to find novel programmable systems, the team began by zeroing in on a structural feature of the CRISPR ...

The alterations included neutering the Cas9 enzyme—which ordinarily cuts DNA—so it would grab the RNA target without cleaving it, and sticking on a fluorescent protein to allow for visual tracking. A ...

Plant breeding plays a vital role in ensuring global food security by increasing crop yields, improving nutritional quality ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...

One of the barriers to using CRISPR-Cas9 gene editing in the clinic is the possibility ... throughout the genome and show in mice that a carefully designed guide RNA strand does not produce any ...

The Cas9 protein is the most widely used by scientists. This protein can easily be programmed to find and bind to almost any desired target sequence, simply by giving it a piece of RNA to guide it ...

Ophthalmology Times - ophthalmology news, articles, and events in a timely and accurate manner for members of the ophthalmic ...

One of the hottest topics in the life science field today is "CRISPR- Cas9". Assistant Professor Hiroshi Nishimasu and his collaborators were the first in the world to report the 3D structure of the ...

In a shining moment for Uganda and the African scientific community, Dr Matthias Magoola, founder of Dei Biopharma, has been ...