Thomas Ostwald and David MacLennan were characterizing proteins that bind to calcium in the sarcoplasmic reticulum — a specialized type of endoplasmic reticulum found in muscle cells.

The new research finds that the endoplasmic reticulum and the plasma membrane form contact sites where specialized molecules ...

The largest calcium store in cells is found in the endoplasmic reticulum/sarcoplasmic reticulum, where CRT and other calcium binding proteins like calsequestrin bind calcium. CRT is responsible ...