Over the past dozen years, treatment approaches in lupus nephritis (LN) have changed substantially, and this is reflected in ...

DelveInsight's "LUPKYNIS Market Size, Forecast, and Market Insight Report" highlights the details around LUPKYNIS, the first ...

Phototherapy with topical antioxidants is the most effective combination for vitiligo, followed by corticosteroids and calcineurin inhibitors.

Figure 1: a, Shift in calmodulin-associated CnA isoforms in the failing human left ventricle. Of the three calcineurin A isoforms (α, β and γ), CnA-β predominates in cardiac muscle. We ...

We previously reported sustained calcineurin (Cn) activation in human lymphoid malignancies, and showed that Cn inhibitors have antileukemic effects in mouse models of T-ALL. It was unclear ...

Preventing this complication for those who receive a lung transplant is of the highest priority, as there are no universally effective treatments for CLAD once it is established. The most common of ...

Findings on tacrolimus use in lung transplant patients, showing its effectiveness over cyclosporine in preventing chronic ...

The most common of the immunosuppressing medications given to lung transplant recipients are calcineurin inhibitors. Only two calcineurin inhibitors exist, cyclosporine and tacrolimus, and the ...

As a novel calcineurin inhibitor with proven efficacy in improving renal outcomes, LUPKYNIS addresses a high unmet medical need. With increasing awareness, supportive guidelines, and potential ...