Scientists at St. Jude Children's Research Hospital have designed new drug frameworks that selectively target CYP3A4, one of the most critical CYP proteins. Structural insights from this work ...

Scientists at St. Jude Children’s Research Hospital have designed new drug frameworks that selectively target CYP3A4, one of the most critical CYP proteins. Structural insights from this work offer a ...

CYP3A4 breaks down drugs that treat various health conditions, including the anti-cancer agent paclitaxel and the COVID-19 therapeutic nirmatrelvir. CYP3A4 inhibitors are commonly co-administered ...