Cytochrome P450 (CYP) proteins are responsible for breaking down more than 80% of all Food and Drug Administration (FDA)-approved drugs, reducing their effectiveness. However, how to prevent CYPs from ...

Some medications and supplements can make your birth control less effective at preventing pregnancy. These include some ...

such as the cytochrome p450 (CYP) and others, that process many types of medications. This is called metabolism. It also has a way to get rid of drugs, usually though your urine. Other drugs may ...

The drug is cleared by cytochrome P450 (CYP)3A4 metabolism. Peak plasma concentrations are achieved about 1.5 hours after oral administration. Its absorption is not affected by food. Eplerenone ...

The level of CYP3A4 expression may determine which patients best respond to certain drugs, and which patients experience side effects or even toxicity when the same dosage is administered.

Potentiated by CYP3A4 inhibitors (eg ... Monitor for hypokalemia with potassium-depleting drugs (eg, amphotericin B, diuretics). Toxic epidermal necrolysis possible with thalidomide.

Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. Very Serious. These medicines may interact and cause very harmful effects and ...

[20] Although both the sulfonylureas and certain fluoroquinolones interact with the CYP isoenzyme system, each proceeds through a different primary pathway. Thus, a drug–drug interaction via CYP ...