In a custom humanized rat model of AATD, SyNTase editing achieved potent gene correction of the E342 mutation with >70% mRNA correction and >3-fold ... The Nobel Prize-winning CRISPR technology has ...

Moreover, innovations in LNP formulations have improved not only their targeting ability, but also their drug-loading ...

If you think last week's decision by the federal government to halt $500 million in funding for vaccine development projects that use mRNA technology will only affect COVID vaccines, think again.

Two recent studies identified gene knockouts that may make CAR T-cell therapy more effective, but the next step is applying the hypotheses in humans.

Preclinical data presented at the European Society of Gene and Cell Therapy (ESGCT) highlight a potential best-in-class profile--The AATD ...

Cells use mRNA to build proteins, and after years of research, scientists learned how to harness this molecule to develop effective, safe and quick-to-make vaccines. Since the advent of this Nobel ...

SAN DIEGO & BRISBANE, Calif.--(BUSINESS WIRE)--VedaBio, a pioneering biotechnology company transforming molecular detection, today announced a non-exclusive license agreement with Mammoth Biosciences, ...

After axing a wide swath of federal research projects and grants, a recent slew of awards offers a glimpse into the kinds of ...

The Influenza A virus (IAV) has been the cause of six major flu pandemics, responsible for 50 to 100 million deaths globally.

The ability to correct disease-causing genetic mistakes using genome editors holds great promise in medicine, but it is not without risk. When this type of “genetic surgery” is performed on DNA, for ...

Unlike CRISPR, this approach makes more specific ... of-the-art [technology], which suggests it could be a safer technology.” He said the new tool also is capable of editing pre-mRNA, the precursor to ...